From The Mind Come Drugs of the Future
17
GPCR & Membrane protein
Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors
관리자
2022-12-08
293
16
Dynamic Behavior of the Active and Inactive States of the Adenosine A2A Receptor
187
15
Structural Dynamics and Thermostabilization of Neurotensin Receptor 1
201
14
Solution structure of the transmembrane 2 domain of the human melanocortin-4 receptor in sodium dodecyl sulfate (SDS)..
195
13
How Do Short Chain Nonionic Detergents Destabilize G‑Protein-Coupled Receptors?
205
12
Conserved Mechanism of Conformational Stability and Dynamics in G‑Protein-Coupled Receptors
185
11
Structure and dynamics of a constitutively active neurotensin receptor
196
10
Leukotriene B4 receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose lig..
190
9
Exploring the Ligand Efficacy of Cannabinoid Receptor 1 (CB1) using Molecular Dynamics Simulations
202
8
Engineering Salt Bridge Networks between Transmembrane Helices Confers Thermostability in G‑Protein-Coupled Recepto..
198
7
Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors
189
6
Structural insights into the subtype-selective antagonist binding to the M2 muscarinic receptor
191
5
Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A2A Receptor
176
4
Elucidation of Mechanism for Ligand Efficacy at Leukotriene B4 Receptor 2 (BLT2)
182
3
Activation Microswitches in Adenosine Receptor A2A Function as Rheostats in the Cell Membrane
223